Visit Neogen at IAFP — Booth #544

By Joe Heinzelmann

The International Association of Food Protection’s (IAPF) annual meeting is taking place this year from Saturday, July 25th — Tuesday, July 28th. The event features leaders from the food safety industry and hosts a wide variety of presentations, workshops and professional development groups.

Neogen will be in attendance at booth #544, showcasing a number of new products including Reveal 3D for Multi Treenut, innovations for ANSR—a molecular pathogen detection platform—and AccuPoint Advance, the latest innovation in hygiene monitoring, By visiting Neogen’s booth you’ll be able to see how the new design of our AccuPoint Advance sampler allows for better recovery, and more accurate results.

Also, if you haven’t picked up a copy of Neogen’s Food Allergen Validation and Verification Handbook, please stop by our booth to do so. This handbook provides guidelines, best practices and sound strategies for validation of allergen control plans, and the routine verification.

In addition, IAFP offers a wide range of educational opportunities. Some of the presentations covered in the meeting can be seen in the schedule overview and include recurring themes in genomics and process control. For example, the new Food Safety Modernization Act and the focus on preventive controls will be covered along with genomic sessions that cover identification methods, whole genome sequencing, next generation sequencing and more.

Examples of these talks include:

We look forward to seeing you at IAFP. If you will be at the event, please register for a time to speak with us here. See you in Portland!

For more information on the conference, click here.

Join Neogen at Engredea 2015

By James Topper

Join Neogen at booth #175 on March 6– 8, 2015 for Engredea 2015 at the Anaheim Convention Center.

Engredea brings together a community of leading suppliers and manufacturers of new
ingredients, packaging, technologies, equipment, and services in the global nutrition industry. Engredea, co-located with Natural Products Expo West, is the only trade show that brings together the full food chain of supply to shelf.

Neogen, a world leader in food safety, is excited to showcase new solutions to facilitate cGMPs, quality assurance programs and verification systems at Engredea. Neogen will be presenting new products that have been validated specifically for natural products, dietary supplements, and other nutritional products.

These include:

  • The BioLumix System
  • Allergen control tests and plans
  • Hygiene monitoring equipment

The BioLumix Rapid Microbiology System delivers significant reduction in time to results, reduced staff involvement, and faster product release. BioLumix can save multiple days versus current testing methods and dramatically impact key profit drivers. The validated BioLumix system allows for easy compliance with cGMP. BioLumix will streamline your microbiological testing saving significant time labor and money. BioLumix delivers shorter sample preparation, automated real-time communication, fast product release and early warning of contamination. It is paperless and efficient, saving on disposables, time and space. The system eliminates product interference, delivering accurate results.

With BioLumix Rapid, Automated Microbiology you can view microbiology product testing from a position of company strength and competitive advantage! Streamline your microbiological testing, reduce cost, increase efficiency and show rapid return on investment. The BioLumix system is FDA compliant, fully automated, validated against USP methodology and 21 CFR Part 11 Compliant. The system delivers complete microbiology testing results within 24-48 hours, allowing for faster product release time, shorter sample prep time – saving time, money and other resources.

Neogen’s allergen testing solutions help companies put together best practices for allergen control Neogen’s industry supported Supplier verification document starts with raw materials. Using testing and best practices, companies can have confidence that ingredients, sanitation teams, and their products all comply with allergen label claims.

AccuPoint Advanced is Neogen’s the newest hygiene monitoring system. It gives users the most complete system, from accurately capturing samples, to generating useful information to drive improvements. Visit Neogen’s booth #125 to hear more about the new system, and see a demonstration to see why the AccuPoint Advance is the right tool for the job.

Environmental Monitoring in the Pharmaceutical & Nutraceutical Industries

FDA expects manufacturers to be in control of the environmental conditions within the manufacturing facility. Controlling the environmental condition is not only a regulatory requirement but also part of protecting and producing a quality product. Environmental monitoring of Pharmaceutical & Nutraceutical manufacturing facilities provides assurance that the environment is in control, and in compliance.  There is substantial evidence establishing a direct relationship between the level of environmental control and the final quality of the product.

A variety of methods are available to measure total particles in the air, Total Organic Carbon (TOC), and ATP (Adenosine Tri-phosphate).  These methods while very fast to perform do not correlate with total bacterial count or any specific group of organisms in many cases.  Therefore, these results do not tell us when we have viable organisms in the environment and on production lines. The standard plating methodologies can take several days for results.  Rapid microbiological methods can provide the solution

Why Not Monitor ATP?

Adenosine-Tri-Phosphate (ATP) is an energy molecule stored in all microorganisms and therefore an indicator of life.  ATP bioluminescence began to gain traction over plate count approaches in the late 1980s, especially in the food industry.  It is basically a “dirt” detector rather than a microorganism detector.   It is a common misconception that the results received from ATP testing systems in relative light units (RLUs) for surface samples should correlate with a microbial total plate count result.

The lack of correlation between ATP and plate counts means that samples can have high ATP readings and no bacteria or conversely have low ATP readings and high bacteria count.  For example, the inside of a tomato is sterile and doesn’t contain bacteria, yet it contains large amounts of ATP.  Likewise, it is possible to have bacteria and still get pass from an ATP based test, because 10,000 bacteria/swab are required for detection.  To complicate the matter further, there are different levels of ATP in different cells on the surface. Yeast, for example, contains 100 times the ATP amount of Coliform bacteria.

The standard used for post-cleaning surface contamination is typically 100 – 1,000 bacteria / 100cm2, and 10-50 yeast and molds which is lower than the detection limit for the ATP test.   Therefore, ATP results do not tell whether the surface is microbiologically acceptable.  In other words, it does not tell how many or what kind of microorganisms or chemical contaminants are present on the surface—only that there is organic matter present on the surface in which microorganisms might be able to grow.  Also, sanitizer residues on food contact surfaces or certain food components may interfere with the ATP reaction.

The BioLumix Advantage

BioLumix is an optical rapid, automated system that simplifies microbiological testing.  The system can be utilized for simplified monitoring of the manufacturing environment. Three assays were tested:  Total Aerobic Count, Total Combined Mold and Yeast Count, and Bile Tolerant Gram Negative Count (Enterobacterial Count).  A study was performed to compare and validate the BioLumix system as an alternative to the standard plate count method in detecting microbial contamination in manufacturers’ production surfaces.  Five different surfaces were used to simulate production surfaces.  10X10 cm coupons were inoculated with microorganisms, allowed to dry and then swabbed.  The swabs were inserted into a diluent (buffer or TSB) and analyzed by both the BioLumix and plate count assays.

A total of 550 coupons were tested, 290 were inoculated with various levels of contamination from <10 to <5,000 cfu/swab. The swabs containing microorganisms above the specified levels showed a very good correlation between the BioLumix and the various plate count results, with an overall agreement for samples above spec of 97.2%.  Almost all the discrepant swabs had plate counts very close to the specified level. None of remaining 260 swabs which contained counts below the specified levels did detect in the BioLumix system.  Consequently there was 100% agreement between the two methods.  The system also has the utility to detect for objectionable organisms such as E. coli, S. aureus and Salmonella.

Therefore, the BioLumix system offers:

  •  Automation of results
  •  Speed
  • Paperless
  • Detects microorganisms and not indicators
  • Can detect multiple types of organisms
  • Increases operation efficiency and consequently, improves quality and reduces costs                 
  • Enhanced reporting and ability to track trends